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August 19, 2025 2 min read

Both are popular monthly chews for dogs. The key difference is what they cover beyond fleas and ticks. Here’s a plain-English comparison so you can choose the one you’ll give on time, every time. Prepared with input from our lead vet and founder, Dr. Feargus McConnell, BVSc.
Simparica Trio: fleas, ticks, heartworm prevention, and common intestinal worms (roundworm & hookworm) in one monthly chew.
NexGard Chewables: fleas & ticks in a simple monthly chew. (No heartworm or intestinal worm coverage — you’ll pair it with a separate worm/heartworm plan.)
Choose Simparica Trio if you want an all-in-one monthly chew that includes heartworm prevention and common intestinal worms as well as fleas and ticks.
Choose NexGard Chewables if you’re after flea & tick only, or you already have a separate heartworm/intestinal worm routine you’re happy with.
Swimmers and bathers: Chews are ideal because they aren’t washed off.
Busy households: One product that covers more jobs (Simparica Trio) can simplify reminders.
Existing schedule: If you’re set up with a separate heartworm tablet/injection plan, NexGard Chewables can slot in neatly for fleas & ticks.
Both are monthly. Set a phone reminder, dose the same date each month, and treat every dog in the home. In tick-risk areas, still do quick daily tick checks.
Match weight band and minimum age. Dog products for dogs only. Don’t stack preventatives unless your vet advises. Ask your vet first if your dog is unwell, pregnant/breeding, or on other meds.
Simparica Trio Chewable Tablet for Dogs — monthly all-in-one when used as directed.
NexGard Chewables for Dogs — monthly fleas & ticks.
Bravecto Chew for Dogs — long-lasting fleas & ticks (handy if you prefer fewer doses).
Which kills fleas faster?
Both are fast-acting when used as directed. Consistency matters most.
Can I switch between them?
Yes. Start the new product when the old one is due to avoid gaps or double-dosing.
Not sure which setup fits your dog and routine?
Tell us your dog’s age, weight and lifestyle and we’ll help you choose — contact us.

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